The opera was first performed on September 16, 1966, at the opening of the new Metropolitan Opera House in Lincoln Center for the Performing Arts in New York City. After an unsuccessful premiere, the opera was extensively revised by Barber and Gian Carlo Menotti in an edition first performed in 1975.

Librettist Franco Zeffirelli (Based on the play Antony and Cleopatra by William Shakespeare and made use of Shakespeare's language exclusively)
Date of composition 1966 (revised in 1975)
Premiered 1966, September 16th (Metropolitan Opera House) in New York, NY, United States
Type Opera
Catalogue Op. 40
Instruments Voice (Soprano) - Cleopatra
Voice (Baritone) - Mark Antony
Voice (Tenor) - Octavius Caesar
Voice (Bass) - Enobarbus
Voice (Mezzo-Soprano) - Charmian, servant to Cleopatra
Voice (Mezzo-Soprano) - Iras
Voice (Tenor) - Mardian
Voice (Tenor) - Messenger
Voice (Bass) - Alexas
Voice (Tenor) - Lepidus
Voice (Baritone) - Canidius
Autotranslations beta Samuel Barber: Antony and Cleopatra, Op. 40
Samuel Barber: Antony and Cleopatra, Op. 40
Samuel Barber: Antony and Cleopatra, Op. 40