There are earlier examples by Luigi Boccherini (two sets of six each). However, between the Boccherini and the Brahms, very few for stringed instruments without piano seem to have been written or published, whereas within the decades following Brahms' two examples, a number of composers, including Antonín Dvořák, Peter Ilyich Tchaikovsky, Joachim Raff, Max Reger, Arnold Schoenberg, and Erich Wolfgang Korngold, all wrote string sextets.

Date of composition 1860
Premiered 1860, October 20th in Hanover, Germany
First published 1862, Simrock
Tonality B-flat Major
Catalogue Op. 18
Instruments 2x Cello
2x Violin
2x Viola
Autotranslations beta Johannes Brahms: String Sextet n°1 en si bémol majeur, Op. 18
Johannes Brahms: String Sextet n. 1 in si bemolle maggiore, Op. 18
Johannes Brahms: String Sextet Nr. 1 B-dur, Op. 18